GFC Hair Treatment: Growth Factor Concentrate Explained (2026 London Guide)
Last updated: March 2026
What is GFC treatment for hair loss?
GFC (Growth Factor Concentrate) is a next-generation hair restoration treatment that extracts and concentrates only the pure growth factors from your own blood, removing platelets, red blood cells, white blood cells, and all other blood components. The result is a highly refined formulation containing concentrated EGF (epidermal growth factor), PDGF (platelet-derived growth factor), IGF-1 (insulin-like growth factor), and VEGF (vascular endothelial growth factor) that is injected directly into the scalp to stimulate dormant follicles, strengthen miniaturising hair, and promote new growth.
GFC is rapidly gaining attention as the next evolution of PRP therapy. While PRP delivers the entire platelet-rich plasma layer (growth factors mixed with platelets and other cells), GFC isolates only the regenerative growth factors themselves, delivering a purer, more concentrated treatment. Early clinical data suggests GFC may produce greater density improvements with fewer sessions than traditional PRP, making it one of the most talked-about advances in non-surgical hair restoration in 2026.
At The London PRP Clinic by The Wellness, GFC is now available from £495 per session, performed by GMC-registered doctors at our Marylebone and Canary Wharf locations.
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How does GFC differ from PRP?
Both GFC and PRP are autologous treatments derived from your own blood. The critical difference lies in what gets injected.
PRP (Platelet-Rich Plasma) concentrates the platelet-rich layer of your blood after centrifuging. This layer contains platelets (which store growth factors), along with some white blood cells, red blood cells, and plasma proteins. When injected, the platelets release their growth factors at the treatment site. PRP has an enormous evidence base: 43 randomised controlled trials involving 1,877 participants confirm it significantly increases hair density by an average of 31% (Anitua et al., 2025). At The London PRP Clinic, PRP achieves an 87% success rate.
GFC (Growth Factor Concentrate) uses a specialised preparation kit containing a platelet-activating solution (developed by Wockhardt Ltd). Your blood is drawn into purpose-built tubes, mixed with the activating solution, and allowed to stand for approximately 30 minutes. During this time, the solution activates the platelets and triggers them to release their growth factors into the surrounding plasma. The tubes are then centrifuged to separate the pure growth factor layer from all blood cells. The final injectable contains only the concentrated growth factors themselves, with no platelets, no red blood cells, and no white blood cells.
This distinction matters because the pure growth factor formulation may reduce the mild inflammatory response that can occur when whole platelets and white blood cells are injected with standard PRP. Researchers suggest this cleaner preparation may allow the growth factors to act more efficiently on follicle cells without competing signals from other blood components.
What does the clinical evidence show?
GFC evidence is early-stage but promising. A 2024 prospective study published in Cureus examined patients with androgenetic alopecia treated with 3 GFC sessions at 4-week intervals. Macroscopic photographs showed significant improvement in hair growth across all treated patients. Trichoscopic analysis confirmed pronounced improvement in hair density alongside decreased shaft diameter variability and fewer yellow dots (a trichoscopic marker of follicular inactivity). The hair pull test was negative in 100% of patients at 8 weeks post-treatment. Patient satisfaction reached 80%, and zero adverse events were recorded.
A separate comparative analysis reported that GFC achieved 37.1 hairs per cm squared of new growth versus 28.4 hairs per cm squared for PRP, though this data requires confirmation in larger trials.
Our honest assessment: PRP has decades of clinical use and 43 RCTs supporting its efficacy. GFC has promising pilot data and growing global adoption, but lacks the depth of randomised controlled evidence that PRP has accumulated. At The London PRP Clinic, our doctors present both options transparently so patients can make informed decisions based on their priorities and preferences.
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How is GFC treatment performed?
The procedure follows a similar structure to PRP but with a different preparation method.
Step 1: Blood collection. Approximately 16 to 25 ml of blood is drawn from your arm into specialised GFC preparation tubes containing a platelet-activating solution.
Step 2: Activation. The tubes are inverted 6 to 10 times to mix the blood with the activating solution, then allowed to stand upright for approximately 30 minutes. During this period, the platelets are activated and release their concentrated growth factors into the plasma.
Step 3: Centrifugation. The tubes are centrifuged at specific speed and temperature settings to separate the pure growth factor layer from all blood cells, platelets, and debris.
Step 4: Extraction. The clear growth factor concentrate layer (approximately 6 to 8 ml of ready-to-inject formulation) is carefully extracted using a sterile syringe. This golden liquid contains pure EGF, PDGF, IGF-1, VEGF, and other growth factors without any cellular contamination.
Step 5: Injection. After the scalp is cleaned and optionally numbed with topical anaesthetic, the GFC is injected subcutaneously across the areas of thinning using a fine needle. The entire appointment takes approximately 60 to 90 minutes.
Who is GFC best suited for?
GFC is most effective for patients with early-to-moderate androgenetic alopecia (Norwood I to IV, Ludwig I to II) where follicles are still active but weakened, patients who want a purer growth factor formulation with potentially fewer sessions than traditional PRP, patients who have had good results with PRP and want to explore the next evolution of the technology, patients who experienced mild inflammatory responses to standard PRP (redness, scalp sensitivity) and may benefit from the cleaner GFC formulation, and patients who want the convenience of fewer total sessions (3 to 4 for GFC versus 4 to 6 for standard PRP).
GFC cannot restore hair in completely bald areas where follicles have been permanently destroyed. In those cases, surgical transplantation is required, with GFC or PRP used as a complement to optimise graft survival.
Can GFC and PRP be combined?
Yes. Because GFC delivers a purer growth factor formulation while PRP delivers a broader biological stimulus (including platelets that continue releasing growth factors over time at the injection site), some protocols alternate GFC and PRP sessions within a treatment plan. This hybrid approach delivers the purity advantages of GFC alongside the sustained-release benefits of whole platelet injection.
At The London PRP Clinic, our doctors can design combined or alternating protocols based on your specific hair loss pattern, treatment response, and preferences. The clinic also offers ExoRevive exosome therapy (from £445), which can be layered with either GFC or PRP for the most comprehensive regenerative approach available.
GFC vs PRP vs ExoRevive: choosing the right treatment
Choose PRP if you want the treatment with the strongest clinical evidence (43 RCTs, 1,877 patients), you value the proven 87% success rate at The London PRP Clinic, and you prefer the most extensively studied autologous approach. PRP from £545 per session.
Choose GFC if you want a purer growth factor formulation without cellular contamination, you want fewer sessions (3 to 4 versus 4 to 6), you experienced mild inflammatory responses to standard PRP, or you want to try the latest evolution of autologous regenerative therapy. GFC from £495 per session.
Choose ExoRevive if you want stem cell-derived regenerative signalling alongside or instead of blood-derived treatments, or you want to add a non-autologous regenerative layer to your PRP or GFC protocol. ExoRevive from £445 per session.
Combine treatments if you want the most comprehensive regenerative approach targeting multiple biological pathways simultaneously.
Your GMC-registered doctor at The London PRP Clinic will recommend the most effective approach based on your specific hair loss pattern, stage, medical history, and goals.
GFC treatment at The London PRP Clinic by The Wellness
GFC from £495 per session. Course of 3 to 4 sessions recommended.
PRP also available from £395 per session. ExoRevive from £445. Combined protocols available.
GMC-registered doctors perform every consultation and treatment. Specialist preparation systems for consistently high growth factor concentrations. Comprehensive diagnostic assessment before any treatment recommendation. 87% success rate across all hair restoration patients. 187+ five-star reviews. Marylebone and Canary Wharf locations.
Book your GFC consultation > WhatsApp | Email: team@thewellnesslondon.com | Call: +44 20 3951 3429
Medical Disclaimer: GFC is an emerging treatment with a growing but still developing evidence base compared to PRP. All treatments at The London PRP Clinic are performed by GMC-registered doctors who provide full informed consent regarding current evidence and realistic expectations. Results vary between individuals. Last reviewed March 2026.