What is PRP treatment for hair loss?

PRP (Platelet-Rich Plasma) treatment for hair loss uses your body's own natural growth factors to revive thinning hair, strengthen follicles and boost new growth. The London PRP Clinic offers doctor-led PRP treatments for hair, scalp, and beard growth with proven results.

Does PRP work for beard growth?

Yes, PRP beard growth treatment is highly effective for filling patchy areas, enhancing beard density, and promoting thicker facial hair. Our doctor-led PRP beard treatment at £395 per session uses platelet-rich plasma to stimulate dormant hair follicles in the beard area.

How much does PRP treatment cost in London?

PRP treatment prices at The London PRP Clinic range from £395 for PRP Hair Signature or Beard PRP single sessions, to £545 for comprehensive treatments. We offer package discounts - for example, 3 PRP Hair sessions cost £1,085 (save £100).

What PRP services are available at The London PRP Clinic?

We offer PRP treatments for hair loss, beard growth, facial rejuvenation, under-eye treatment, knee joint pain, and scalp health. All treatments are doctor-led and evidence-based, delivered at our Marylebone, Canary Wharf, and Belgravia London locations.

How much does PRP cost for hair loss in London?

At The London PRP Clinic, PRP hair treatment costs £545 per session including Viviscal™ supplements and organic oils. Most patients need 3-4 initial sessions (package available at £1,500, saving £135). ExoRevive exosome treatment is £445 per session.

Does PRP really work for hair loss?

Yes, clinical studies show PRP is 70-90% effective for androgenetic alopecia. At our clinic, 87% of patients report significant improvement with an average 32% increase in hair density after 3-4 sessions. Results are best for Norwood stages 1-4.

What's better PRP or hair transplant?

PRP is ideal for early-stage hair loss (Norwood 1-4): non-surgical, no downtime, £545 per session. Hair transplants suit advanced loss (Norwood 5-7): permanent but surgical, 2-week recovery, £3,000-15,000. Many combine both for optimal results - PRP strengthens existing hair and enhances transplant survival.

How long do PRP results last?

PRP results typically last 12-18 months with proper maintenance. After initial 3-4 sessions, maintenance treatments every 6 months sustain results. Some patients using our combined protocol (PRP + supplements) report results lasting up to 2 years.

Is PRP painful for hair?

PRP involves minimal discomfort. We use topical numbing cream 30 minutes before treatment. Most patients rate pain as 2-3/10, describing it as 'mild pinching.' The entire procedure takes 60 minutes with no downtime - you can return to work immediately.

Can I wash my hair after PRP?

Wait 24 hours before washing your hair after PRP. Use lukewarm water and gentle shampoo for the first wash. Avoid swimming pools, saunas, and intense exercise for 48 hours. We provide detailed aftercare instructions and organic hair oil for optimal healing.

What are the newest hair loss treatments in 2025?

The newest effective hair loss treatments in 2025 include low-dose oral minoxidil (2.5-5mg daily), topical finasteride (0.25%), platelet-rich plasma (PRP) therapy, and low-level laser therapy devices. Emerging treatments like JAK inhibitors and topical androgen receptor antagonists are showing promising results in clinical trials.

Does oral minoxidil work for hair loss?

Yes, low-dose oral minoxidil (2.5-5mg daily) has proven highly effective for both male and female pattern hair loss. Studies show it's particularly effective for overall thinning, with manageable side effects primarily limited to mild hypertrichosis (extra hair growth).

Is PRP effective for hair restoration?

Yes, PRP therapy has demonstrated significant improvement in hair count and thickness in clinical trials. Most patients see noticeable results after 3-4 sessions, using the body's own growth factors to stimulate dormant hair follicles.

What's the best hair loss treatment in London?

The best hair loss treatment depends on your specific condition, but combination therapy often yields optimal results. The London PRP Clinic offers personalised treatment plans combining PRP therapy with other evidence-based treatments. Book a free consultation to determine the best approach for your hair loss pattern.

How much does PRP hair treatment cost in London?

PRP hair treatment costs vary based on the number of sessions needed. The London PRP Clinic offers competitive pricing with free initial consultations. Contact us via WhatsApp for a personalised quote based on your specific treatment needs.

How Long Does PRP Last, and When Should YouRepeat It

14 Sept

Written By Guest User

For knee osteoarthritis, benefit usually peaks within 6 months and holds for 6 to 12 months, where most trials stop measuring. One 610-patient trial found benefit still present at 5 years after a single course. A repeat is reasonable when the first course helped and has faded, not on a calendar, and not when the first course did nothing.

Key points

A 2026 network meta-analysis in the Journal of Orthopaedic Surgery and Research of 21 randomisedtrials and 2,254 knee patients advised clinicians to counsel patients that peak benefit is likely within 6months and that repeat treatment may be considered after that.
A 2022 multicentre double-blind trial in Knee Surgery, Sports Traumatology, Arthroscopy randomised 610patients to 3 sessions of pure PRP or sham saline and found the PRP group ahead on WOMAC pain,function and total score at 6, 12, 24 and 60 months.
A 2023 systematic review and meta-analysis of 31 randomised trials in Archives of Orthopaedic andTrauma Surgery found PRP performed better in early knee osteoarthritis than in advanced stages, which is the largest single predictor of how long a course lasts.
In hip osteoarthritis, a systematic review of 5 randomised trials found a single injection outperformed a course of multiple injections, so more sessions do not reliably mean longer benefit.

If you have had PRP before and are wondering whether to have it again, message us on WhatsApp or email team@thewellnesslondon.com and a doctor will look at what you had and how it went before recommending anything.

What the trials measure, and what they stop measuring

Most PRP trials follow patients for 6 or 12 months, so most of what is known about duration comes from thatwindow. The pattern across knee osteoarthritis is consistent. Little difference from comparators in the first 4to 6 weeks, a clear difference by 3 months, the largest difference at 6 months, and in the trials that continue, abenefit that is still present but narrowing at 12 months. The 2026 network meta-analysis of 21 trials and 2,254patients summarised this as peak benefit within 6 months, with repeat treatment to be considered after it.

The tendon trials show a longer tail against steroid, because steroid fades. In tennis elbow across 26 trials PRPwas ahead beyond 6 months, and in gluteal tendinopathy an 80-patient trial found PRP sustained at 2 yearswhile steroid was gone by 24 weeks. Those are comparisons with a treatment that wears off, so they describehow long PRP outlasts steroid rather than how long PRP lasts on its own, and placebo-controlled trials in both conditions found no advantage over saline. For duration, the knee osteoarthritis placebo trials are the honest measure, and they mostly stop at a year.

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The one trial that followed patients for 5 years

The exception is a 2022 multicentre double-blind trial in Knee Surgery, Sports Traumatology, Arthroscopy thatrandomised 610 patients with knee osteoarthritis to 3 weekly sessions of pure PRP at 4.3 times the plateletconcentration of whole blood, or 3 sessions of sham saline. It is the largest placebo-controlled PRP trialpublished, and it followed patients to 60 months. At 6, 12, 24 and 60 months the PRP group scored better thanplacebo on WOMAC pain, function and total score. The authors read it as durable benefit from a single course.

Two things about that trial matter for a patient deciding whether to repeat. The product was a high-concentration, leukocyte-poor preparation, and a 2025 meta-analysis of 26 trials found higher plateletconcentrations gave greater improvement, so a weaker product may not last as long. And the patients weremostly earlier-stage disease, which is where the 31-trial meta-analysis found PRP performs best. A 5-yearresult from a strong product in an early knee does not transfer to a low-concentration product in a bone onbone one, and a clinic quoting 5 years should be asked which product and which patients.

Send your previous PRP details and knee imaging on WhatsApp and a doctor will tell you what duration isrealistic for your product and stage.

What decides how long it lasts

Four things explain most of the variation between the patient whose course held for 2 years and the patientwhose course faded in 3 months. Stage of disease is the first and largest. The 2023 meta-analysis of 31randomised trials found PRP performed better in early knee osteoarthritis than advanced disease, and a 2026meta-regression in Knee Surgery, Sports Traumatology, Arthroscopy found younger age improved short-termoutcomes. The product is the second, with concentration and leukocyte content both influencing results.

What happens between courses is the third. A 2026 meta-analysis in Disability and Rehabilitation of 6randomised trials and 314 patients found structured exercise after PRP reduced pain more than PRP alone inthe first 6 months and beyond, which means a patient who keeps loading the joint sensibly holds the benefitlonger than one who stops. Body weight, the demands of work and sport, and whether anti-inflammatorieswere avoided around the injection are the fourth group, and they are the ones you control. A retrospectivesurvival analysis in International Orthopaedics found patients receiving PRP delayed knee arthroplastycompared with expected timelines, which is duration measured in a different currency.

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When to repeat, and when not to

The right time to repeat is when the first course helped and the benefit has faded. That usually means 6 to 12months after the last injection, sometimes longer, and it is judged on symptoms rather than the calendar. Apatient who is still doing well at a year has no reason to repeat, and a clinic proposing annual maintenanceinjections regardless of symptoms is selling a subscription rather than treating a joint.

The wrong time to repeat is when the first course did nothing. A course that produced no change at 6 monthsis information, and the most likely explanations are a stage of disease PRP does not help, a product that wastoo weak, a missed target, or a condition where placebo-controlled trials are negative. None of those is fixedby the same injection again. The hip evidence is the clearest warning against assuming more is better. Thesystematic review of 5 randomised trials found a single injection outperformed a course of multiple injections.A repeat should be a decision by a doctor who has looked at why the first course worked or did not, andchanged something if it did not.

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A repeat decision checklist

Work through this before booking a second course anywhere, including here.

Did the first course help, and for how long. If it did not help at 6 months, do not repeat the same thing.
Has the benefit faded, or is this a calendar reminder. Repeat on symptoms, not dates.
What stage is the joint now, and has it progressed since the first course. Advanced disease responds lessand for shorter.
What product was used, and what concentration. A weak product that faded early is a reason to changeproduct, not to repeat it.
Was the first course followed by a loading programme, and has that continued. If not, that is the first thingto change.
Has anything changed medically, such as new anticoagulants, an infection or a new diagnosis, that altersthe safety picture.
What is the plan if the second course fades faster than the first. Two fading courses usually mean the jointhas moved on and the conversation is surgical.

Our doctors put it this way. A repeat PRP course is a good idea when the first one earned it. It is a bad ideawhen the first one did nothing, and a worse idea when it is sold on a schedule. The joint decides thetiming, not the clinic.

Message us on WhatsApp with what you had, when, how it went, and any imaging, and a doctor will give youa straight answer.

What repeating PRP does not do

A repeat course does not turn a non-responder into a responder, does not regrow cartilage, and does not slowthe progression of osteoarthritis in any way the trials have shown. It does not work better because it is thesecond course, and in the hip a single injection outperformed multiple. There is no evidence for the annualmaintenance injections some clinics sell, and no evidence for repeat intraosseous courses. The 5-year resultcomes from one trial, one product and mostly early disease. PRP is not routinely commissioned by the NHSand private medical insurance rarely covers it, so each repeat is a self-pay decision that deserves the sameassessment as the first.

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What a repeat course costs, and what a scheduled one costs

Specialist central London clinics commonly charge from around £780 to £900 or more per image guided PRPinjection including assessment, with a course of 2 to 3 taking a plan past £2,000. Outside central London PRPis advertised from around £250 to £500, and maintenance packages of 2 or 3 injections a year are common atthat end of the market.

The reframing is arithmetic. A single course that holds for 12 months and is repeated when it fades costs onecourse a year at most. A maintenance package of 3 injections a year, sold regardless of symptoms, costs 3courses for a benefit the trials say peaks at 6 months and is not improved by more sessions. Over 3 years thedifference is thousands of pounds, and the trial with the longest follow up found a single course of the rightproduct still working at 5.

Care at The London PRP Clinic by The Wellness is doctor-led and priced below flagship central London rates,with your exact figure confirmed at the free suitability review once a doctor has looked at your first course anddecided whether a second is warranted.

Ask about the cost of a repeat course on WhatsApp and we will explain what the review covers.

The free suitability review

Every enquiry here starts with a free, doctor-led suitability review rather than a booking. For a repeat coursethat means a GMC-registered doctor going through what was injected, when, how long it helped, what haschanged in the joint since, and what you have done between courses, and then giving one of two answers.Either you are approved for a further course, with a stated product, a stated number of injections and realisticexpectations for how long it should hold, or you are not approved, with an honest explanation of why a repeatwould not help and what would.

We decline a meaningful share of the people who enquire. That is deliberate. A clinic that approves everyone isoptimising for bookings, not outcomes.

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Why people choose The London PRP Clinic by The Wellness

An 87 percent patient success rate across treatments.
More than 187 five star reviews.
Every treatment performed by a GMC-registered doctor.
100 supervised treatments completed by every clinician before they treat a patient here unsupervised.
A 32 percent average density increase reported in our hair restoration programme.

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Frequently asked questions

How long does PRP last for knee arthritis

Benefit peaks within 6 months and usually holds for 6 to 12 months, according to a 2026 network meta-analysis of 21 trials. One 610-patient trial of high-concentration PRP found benefit still present at 5 years.Earlier-stage disease and a stronger product last longer.

How often can you have PRP injections

When the previous course helped and has faded, usually 6 to 12 months or more after the last injection. Thereis no evidence for repeating on a fixed schedule, and in the hip a single injection outperformed multiple.Repeat on symptoms, with a doctor’s assessment, not on a calendar.

Does PRP work better the second time

No. A second course does not work better because it is the second, and if the first did nothing at 6 months thesame injection again is unlikely to help. A repeat makes sense when the first course worked and has worn off,or when something specific, such as the product or the guidance, is being changed.

Do you need maintenance PRP injections every year

There is no trial evidence for maintenance injections given regardless of symptoms. The right approach is torepeat when benefit fades. Some patients need a course a year, some go longer, and the largest placebo-controlled trial found a single course still working at 5 years.

Why did my PRP wear off quickly

The usual reasons are advanced disease, which responds less and for shorter, a low-concentration product, amissed target, or no loading programme afterwards. A course that faded within 3 months is a reason tochange something before repeating, not to repeat the same thing.

Can PRP delay the need for surgery for years

Sometimes. A survival analysis in International Orthopaedics found PRP delayed knee arthroplasty, and the610-patient trial found benefit at 5 years. Those results come from earlier disease and strong products. Inadvanced disease PRP is a bridge measured in months, not years, and a surgeon should stay in the picture.

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References

Journal of Orthopaedic Surgery and Research, 2026. Leukocyte-rich versus leukocyte-poor platelet-richplasma and hyaluronic acid for knee osteoarthritis, a systematic review and network meta-analysis of 21randomised trials. https://link.springer.com/article/10.1186/s13018-026-06689-4
Knee Surgery, Sports Traumatology, Arthroscopy, 2022. Long-term clinical efficacy of pure platelet-richplasma versus sham saline in knee osteoarthritis, a multicentre double-blind randomised trial of 610participants. https://delosportsmedicine.com/wp-content/uploads/2022/03/PRPLongTermEfficacyArticle.pdf
Archives of Orthopaedic and Trauma Surgery, 2023. Vilchez-Cavazos et al. The use of platelet-richplasma in studies with early knee osteoarthritis versus advanced stages of the disease, a systematicreview and meta-analysis of 31 randomised clinical trials. Cited at https://www.dovepress.com/current-perspectives-on-platelet-rich-plasma-injections-for-knee-osteo-peer-reviewed-fulltext-article-OAJSM
Cureus, 2024. Almutairi and Alazzeh. Efficacy and safety of PRP intra-articular injections in hiposteoarthritis, a systematic review of randomised clinical trials.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11578636/
Journal of Experimental Orthopaedics, 2025. Platelet-rich plasma compared to viscosupplementation inthe treatment of knee osteoarthritis, a meta-analysis of 26 randomised trials. Summary athttps://myorthoevidence.com/AceReport/Show/platelet-rich-plasma-compared-to-viscosupplementation-in-the-treatment-of-knee-osteoarthritis
Knee Surgery, Sports Traumatology, Arthroscopy, 2026. Younger age and platelet-rich plasmacharacteristics influence short-term outcomes in knee osteoarthritis, a systematic review with meta-analysis and meta-regression. https://pubmed.ncbi.nlm.nih.gov/42605960/
Disability and Rehabilitation, 2026. Dasdemir et al. The effect of combined platelet-rich plasma andexercise on pain and function in knee osteoarthritis, a systematic review and meta-analysis of randomisedcontrolled trials. https://pubmed.ncbi.nlm.nih.gov/42188836/
International Orthopaedics, 2020. Platelet-rich plasma injections delay the need for knee arthroplasty, aretrospective study and survival analysis. https://link.springer.com/article/10.1007/s00264-020-04669-9
Central London clinic price lists for image guided PRP and steroid injections, accessed September 2026.

This article is for general information and does not replace a medical assessment. Speak to one of our doctorsbefore deciding whether to repeat PRP.

Reviewed by [GMC-REGISTERED DOCTOR NAME, GMC NUMBER TO CONFIRM], The London PRP Clinic byThe Wellness. Last updated September 2026.

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