Alopecia Areata Treatment London. JAK Inhibitors, Steroid Injections And PRP

Alopecia areata is an autoimmune condition in which the immune system attacks hair follicles, usually causing round, smooth bald patches. Because the follicles are not destroyed, hair can regrow. For patchy disease, steroid injections are standard, and PRP is a steroid-free option with comparable results in trials. For severe disease, new oral JAK inhibitors are available, and a third was approved in the UK in March 2026.

Key points

  • Alopecia areata does not scar, so the follicles remain and regrowth is possible, sometimes without any treatment.

  • A 2022 meta-analysis of randomised trials found no significant difference in scalp hair regrowth between PRP and steroid injections, and two trials reported lower relapse rates with PRP.

  • NICE recommends the JAK inhibitor ritlecitinib for severe alopecia areata, defined as at least 50% scalp hair loss, in people aged 12 and over.

  • The MHRA approved deuruxolitinib for severe alopecia areata in adults on 12 March 2026, and NICE's decision on NHS use is due in October 2026.

Patchy hair loss? Message a GMC-registered doctor on WhatsApp or email team@thewellnesslondon.com.

What alopecia areata is

The condition

The immune system mistakenly attacks the base of the hair follicle and pushes it into a resting state. Hair falls out, typically in round or oval smooth patches on the scalp, beard or eyebrows. Short broken hairs that narrow towards the scalp, sometimes called exclamation mark hairs, are a characteristic sign.

It can affect anyone at any age. It is more common in people with other autoimmune conditions, particularly thyroid disease, and in people with eczema or a family history of the condition.

How it behaves

Many small patches regrow on their own within months. Others persist, spread or recur. A minority progress to loss of all scalp hair, known as alopecia totalis, or all body hair, known as alopecia universalis. Severity is measured with the SALT score, the percentage of scalp hair lost.

Why diagnosis matters

Patchy hair loss is not always alopecia areata. Fungal infection of the scalp, hair pulling, traction and early scarring alopecia can all look similar. Scarring conditions destroy follicles permanently and need different treatment urgently. Dermoscopy, and occasionally a biopsy, settles the question. Our guide to the different types is what type of hair loss do I have.

Treatment by severity

Small patches

Waiting is reasonable for a few small patches, because many regrow on their own. Strong topical steroids are sometimes used.

The most established treatment for patchy disease is steroid injected into the patches, usually repeated every 4 to 6 weeks. It is effective for many people. Repeated injections can thin the skin at the injection site.

PRP as a steroid-free option

PRP uses growth factors from your own blood and is injected into the patches in the same way. A 2022 systematic review and meta-analysis in Biomedicines pooled 4 randomised controlled trials covering 201 patients. It found no significant difference in scalp hair regrowth between PRP and steroid injections.

Individual trials pointed in PRP's favour on relapse. In one, relapse at 12 months was 31% after PRP against 71% after steroid. In another, relapse at 6 months was 5% after PRP against 25% after steroid. Skin thinning was reported with steroid, while PRP injections were more uncomfortable.

The authors called PRP a promising steroid-free option and said larger, high-quality trials are still needed. That is a fair summary. PRP suits people who have had skin thinning from steroid, want to avoid repeated steroid, or have relapsed after it.

Want to know which suits your patches? Ask our doctors on WhatsApp.

Severe or extensive disease

For widespread loss, oral JAK inhibitors have changed what is possible. They block the immune signals that attack the follicle.

Ritlecitinib is recommended by NICE, in guidance published in March 2024, for severe alopecia areata in people aged 12 and over. Severe means a SALT score of 50 or more.

Deuruxolitinib was approved by the MHRA on 12 March 2026 for severe alopecia areata in adults. In its trials, around 30% of people had 80% or more of their scalp hair after 24 weeks, and around 23% had 90% or more. NICE's decision on whether the NHS will fund it is due in October 2026.

Baricitinib is a third JAK inhibitor used for severe disease.

JAK inhibitors are specialist medicines. They need monitoring with blood tests and carry recognised risks, and hair loss often returns if they are stopped. They are initiated by consultant dermatologists. For severe disease, the right step is a dermatology referral, which we can write for you with the tests already done.

What to test

Free to take to any doctor.

Full thyroid function with thyroid antibodies, because autoimmune thyroid disease is associated with alopecia areata.

Full blood count, ferritin and iron studies, vitamin D, B12 and zinc, since deficiencies are common and can slow regrowth.

HbA1c and other autoimmune screening where your history suggests it.

The full panel and why each marker matters is in the hair loss blood panel.

What you can do meanwhile

Take photographs of each patch in the same light every 2 to 4 weeks. It shows whether patches are regrowing, spreading or stable, and helps any doctor you see.

Look after the scalp. Bald skin burns easily, so use sun protection or a hat.

Look after your wellbeing. Alopecia areata can be distressing, and Alopecia UK offers support groups and information.

Be wary of expensive unproven treatments sold with guarantees. The honest position is that the condition is unpredictable, and nobody can promise regrowth.

What treatment costs in London

Flagship Harley Street and Mayfair clinics commonly charge £600 to £850 or more per PRP session, and London practices generally charge 50 to 70 percent more than clinics outside the capital. Patchy alopecia areata often needs several sessions spaced 4 to 6 weeks apart. JAK inhibitors are expensive specialist medicines. Where NICE recommends them, they are prescribed through NHS dermatology.

Our care is doctor-led and priced below flagship rates, with your plan and the figure confirmed after your free suitability review. Blood testing is run from the same clinic.

Ask what your plan would cost. Message us on WhatsApp.

The suitability review

Every enquiry begins with a free doctor-led suitability review rather than a booking. A GMC-registered doctor examines the patches with dermoscopy to confirm the diagnosis and exclude scarring or infection, arranges the relevant blood tests, and gives one of two answers.

Approved for treatment, with a plan for patchy disease, whether steroid injections, PRP or monitoring. Or not approved, with an honest explanation of what would serve you better. For severe disease that is usually a referral to a consultant dermatologist for JAK inhibitor assessment, with your results attached.

Why people choose The London PRP Clinic by The Wellness

The London PRP Clinic by The Wellness is a doctor-led, blood-test-first clinic at 10 Portman Square in Marylebone and the Light Centre in Belgravia. Every treatment is performed by GMC-registered doctors. No clinician treats a patient here until they have completed 100 supervised treatments.

Because we diagnose before we treat, the conditions that mimic alopecia areata are found rather than missed. Across our work we report more than 187 five-star reviews. Every treatment we offer is set out in PRP treatment London, and the newest hair loss drugs are covered in new hair loss treatments 2026.

Book your free suitability review. Message us on WhatsApp, email team@thewellnesslondon.com, or call +44 20 3951 3429.

Frequently asked questions about alopecia areata

Does hair grow back with alopecia areata?

Often, yes. The condition does not destroy the follicles, so regrowth is possible, and many small patches regrow on their own within months. It can recur.

What is the best treatment for patchy alopecia areata?

Steroid injections into the patches are the most established treatment. PRP is a steroid-free option that showed no significant difference in regrowth against steroid in a 2022 meta-analysis of randomised trials.

Does PRP work for alopecia areata?

A 2022 meta-analysis of 4 randomised trials and 201 patients found similar regrowth to steroid injections, and two trials reported lower relapse with PRP. Larger trials are still needed.

What are JAK inhibitors for alopecia areata?

Oral medicines that block the immune signals attacking the follicle. Ritlecitinib is NICE-recommended for severe disease in people 12 and over, and deuruxolitinib was approved by the MHRA in March 2026 for adults.

Is deuruxolitinib available on the NHS?

NICE's decision on NHS funding is due in October 2026. It was approved by the MHRA for severe alopecia areata in adults on 12 March 2026.

What blood tests should I have for alopecia areata?

Full thyroid function with antibodies, full blood count, ferritin and iron studies, vitamin D, B12 and zinc, plus other autoimmune screening where your history suggests it.

This article is for information and does not replace personal medical advice. JAK inhibitors are specialist medicines initiated by consultant dermatologists. Alopecia areata is unpredictable and individual results vary. All treatments at The London PRP Clinic by The Wellness are performed by GMC-registered doctors. Medically reviewed by the GMC-registered medical team at The London PRP Clinic by The Wellness. Last updated September 2026.

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