EZ Gel vs Dermal Fillers: Which Is Right for Your Face?
EZ Gel vs Dermal Fillers: Which Is Right for Your Face?
Not all facial fillers work the same way. Understanding the difference between synthetic fillers and autologous bio-fillers like EZ Gel helps you choose the treatment that aligns with your goals.
The Fundamental Difference
Traditional dermal fillers are synthetic products—most commonly hyaluronic acid (HA)—manufactured in a lab and injected to physically occupy space under your skin. They create immediate volume but do nothing to improve your skin's underlying health.
EZ Gel, by contrast, is a bio-filler created from your own blood. It provides volume and stimulates your body's natural healing response, triggering collagen production and tissue regeneration that continues long after the initial gel has been absorbed.
How They Work
Hyaluronic Acid Fillers
HA fillers are gel-like substances that attract and bind water molecules, creating a plumping effect. They sit in the tissue as an inert substance until your body gradually breaks them down over 6-18 months, depending on the product.
EZ Gel Bio-Filler
EZ Gel combines heated albumin plasma with platelet-rich fibrin (PRF) from your blood. When injected, it acts as a scaffold that releases growth factors—VEGF, PDGF, TGF-beta, collagen 1, and fibronectin—which signal your cells to produce new collagen and blood vessels.
Research shows this leads to measurable improvements in skin density, with one study documenting a 5.08-fold increase in periorbital skin density after just three treatments.
Comparing Safety Profiles
Allergic Reactions
Because EZ Gel uses only your own biological material, the risk of allergic reaction is virtually zero. HA fillers, while generally safe, carry a small risk of hypersensitivity or granuloma formation.
Vascular Complications
Both treatments carry theoretical risk of vascular occlusion if injected incorrectly. However, EZ Gel's lower viscosity and use of blunt cannulas may reduce this risk. Clinical studies report no serious vascular events with EZ Gel.
Longevity of Safety
HA fillers can migrate over time or create visible lumps if placed incorrectly. EZ Gel integrates with your tissue and biodegrades naturally, leaving behind newly formed collagen rather than residual synthetic material.
Results: Immediate vs Progressive
Hyaluronic Acid: Maximum result immediately after injection. Effect gradually diminishes as filler breaks down.
EZ Gel: Moderate immediate volume with progressive improvement over 8-24 weeks as collagen forms. A 24-week study showed patients continued improving through month 6, with 92.3% reporting visible enhancement.
Duration of Results
HA Fillers: 6-18 months depending on product and location.
EZ Gel: The gel itself lasts 3-6 months, but the collagen regeneration it triggers can persist 12-18 months or longer. Studies show the majority of patients maintained results at 2-month follow-up, with benefits extending beyond the gel's absorption period.
Cost Considerations
HA fillers typically cost £300-600 per syringe in the UK. EZ Gel treatments range from £395-595 per session.
While per-session costs are similar, EZ Gel's regenerative benefits may provide better long-term value, as you're building your own collagen rather than temporarily renting volume from a synthetic product.
Which Should You Choose?
Choose HA Fillers If:
You want maximum immediate volume
You're treating very deep folds or significant volume loss
You need a precisely sculpted result
You want results that are easily reversible
Choose EZ Gel If:
You prefer natural, autologous treatments
You want to improve skin quality, not just add volume
You have mild to moderate volume loss
You're concerned about synthetic materials or allergies
You want progressive, natural-looking enhancement
Ready to Make Your Decision?
The best treatment is the one that aligns with your values and goals. That's why a proper consultation matters.
We'll discuss your concerns, explain your options, and recommend the approach that makes sense for your skin and preferences.
Frequently Asked Questions
Can you combine EZ Gel with HA fillers?
Yes. Some patients use HA for structural volume in areas like cheeks, then add EZ Gel for skin quality and subtle volume in delicate areas like under-eyes.
Is EZ Gel FDA approved?
EZ Gel falls under autologous blood product regulations. Because it uses your own blood components, it doesn't require the same regulatory pathway as synthetic fillers.
How long is the consultation?
Your initial consultation is typically 20-30 minutes. We'll assess your skin, discuss your goals, and answer all your questions before recommending a treatment plan.
