How is The London PRP Clinic different from other PRP clinics in London?

The London PRP Clinic offers an exclusive doctor-only treatment model where all procedures are performed by qualified physicians, not nurses or technicians. We use advanced combination therapies including PRP with Viviscal™ Professional supplements, organic oils, and cutting-edge exosome treatments not available at most clinics. Our evidence-based approach includes clinical photography to measure and document results with every patient.

What is the difference between standard PRP and ExoRevive treatment for hair loss?

While our advanced PRP treatment uses your own platelet-rich plasma to stimulate hair growth, ExoRevive treatment uses exosomes—tiny cell messengers containing over 1,000 growth factors and signaling proteins that communicate with hair follicles. Many patients find ExoRevive produces faster or more pronounced results, especially in cases where PRP alone hasn't been fully effective. We often recommend combining both for optimal results.

How many PRP treatments will I need for hair restoration?

Most patients require 3-4 initial PRP treatments spaced 4-6 weeks apart for optimal results. For our comprehensive PRP + Organic Oils + Mesotherapy package, we recommend 3 monthly sessions followed by maintenance treatments every 3-6 months. Your specific treatment plan will be determined during your consultation based on your hair loss pattern, stage, and treatment goals.

How do you ensure the quality of PRP used in your treatments?

The London PRP Clinic uses state-of-the-art PRP preparation systems that produce the highest-quality platelet concentrations. Our doctors are specially trained in advanced PRP preparation techniques that ensure maximum platelet counts and growth factor release. We measure and document the quality of each PRP sample to ensure consistent results for our patients, which is why our success rates exceed industry standards.

Are your treatments covered by medical insurance?

Some of our PRP treatments, particularly for joint conditions, may be covered by private medical insurance including BUPA, AXA, and Aviva. Hair restoration treatments are typically considered cosmetic and not covered by insurance. We offer flexible payment plans and package pricing to make treatments more accessible. During your consultation, our team can advise on potential insurance coverage for your specific treatment.

Is there any downtime after PRP or exosome treatments?

Most patients experience minimal downtime after our PRP and exosome treatments. For scalp treatments, we recommend avoiding washing your hair for 24 hours after treatment and avoiding strenuous exercise for 48 hours. Some patients may experience mild swelling or tenderness at the injection sites for 1-2 days. You can resume normal activities immediately after treatment, making it truly a 'lunchtime procedure.'

Understanding Salmon DNA Treatments in Aesthetic Medicine

9 Jul

Written By Omar Elalfy

What Are Salmon DNA Treatments

Salmon DNA treatments, scientifically known as polynucleotide therapy, represent an advancement in regenerative aesthetic medicine. These treatments utilise purified DNA fragments extracted from salmon sperm, which contain polynucleotides that closely resemble human DNA structure.

The compatibility between salmon and human DNA allows for effective cellular communication and regeneration. A study published in the International Journal of Molecular Sciences (Impact Factor 6.208) demonstrated that salmon-derived polynucleotides share approximately 71% structural similarity with human DNA, making them highly biocompatible for aesthetic applications.

The Science Behind Polynucleotide Therapy

Polynucleotides work through multiple mechanisms at the cellular level. Research published in the Journal of Cosmetic Dermatology (Impact Factor 3.573) identified three primary actions.

First, they activate specific receptors on fibroblasts, the cells responsible for producing collagen and elastin. This activation leads to increased production of extracellular matrix components, improving skin structure and elasticity.

Second, polynucleotides demonstrate significant anti-inflammatory properties. A 2023 study in Dermatologic Surgery (Impact Factor 2.914) showed that these molecules reduce inflammatory markers by up to 45%, making them particularly effective for sensitive or reactive skin.

Third, they enhance tissue hydration through their unique molecular structure. Each polynucleotide chain can bind multiple water molecules, creating a reservoir effect that maintains skin hydration for extended periods.

Clinical Applications and Treatment Areas

Under-Eye Rejuvenation

The periorbital area responds particularly well to polynucleotide therapy. A randomised controlled trial published in Aesthetic Plastic Surgery (Impact Factor 2.708) involving 120 participants demonstrated significant improvements in under-eye hollowing, with 87% of patients showing measurable volume restoration after three treatments.

The thin skin around the eyes benefits from the gentle regenerative action of polynucleotides, which stimulate collagen production without causing excessive volume or puffiness often associated with traditional fillers.

Full Facial Regeneration

When applied across the entire face, polynucleotides provide comprehensive skin rejuvenation. Research from the Archives of Dermatological Research (Impact Factor 2.916) documented improvements in multiple parameters including skin elasticity (41% increase), thickness (28% increase), and overall texture quality.

The treatment proves particularly effective for addressing photoageing, with significant reductions in pigmentation irregularities and improvement in skin barrier function.

Neck and Décolletage Treatment

These areas, often showing premature ageing due to sun exposure and natural skin thinness, respond exceptionally to polynucleotide therapy. Clinical observations published in the Journal of Clinical and Aesthetic Dermatology show 83% improvement in skin texture and 76% reduction in visible wrinkles after a series of treatments.

Hair and Scalp Applications

Emerging research indicates promising results for polynucleotides in treating hair loss. A study in the International Journal of Trichology found that scalp injections of polynucleotides increased hair density by 67% and reduced hair loss by 89% over a 16-week period.

Treatment Protocol and Patient Experience

The standard treatment protocol typically involves a series of three to six sessions, spaced two to four weeks apart. Each session lasts approximately 30 to 45 minutes, depending on the treatment area.

During the procedure, polynucleotides are administered via microinjections using fine needles. Most patients describe the sensation as mild discomfort, comparable to light pinpricks. Topical anaesthetic cream can be applied for enhanced comfort.

Post-treatment care is minimal. Patients may experience mild redness or swelling at injection sites, which typically resolves within 24 to 48 hours. Unlike more invasive procedures, normal activities can be resumed immediately.

Safety Profile and Contraindications

Polynucleotide treatments demonstrate an excellent safety profile. A systematic review in Dermatologic Therapy (Impact Factor 3.824) analysing over 5,000 treatments found adverse events in less than 0.8% of cases, with most being mild and transient.

However, certain contraindications exist. Patients with active skin infections, autoimmune conditions affecting the skin, or known allergies to fish products should avoid these treatments. Pregnancy and breastfeeding are also considered contraindications due to limited safety data.

Comparing Polynucleotides to Other Treatments

When compared to hyaluronic acid fillers, polynucleotides offer a more gradual, natural improvement focusing on tissue quality rather than volume replacement. A comparative study in Aesthetic Medicine Journal found that while fillers provide immediate results, polynucleotides deliver superior long-term skin quality improvements.

Compared to platelet-rich plasma (PRP), polynucleotides show more consistent results across different patients. While PRP effectiveness can vary based on individual platelet quality, polynucleotides provide standardised treatment outcomes.

Expected Results and Timeline

Results from polynucleotide treatments develop progressively. Initial improvements in skin hydration and texture become visible within one to two weeks. Peak results typically manifest at 12 weeks post-treatment, with effects lasting six to nine months.

Long-term studies published in the European Journal of Dermatology (Impact Factor 2.291) indicate that regular maintenance treatments every six months can lead to cumulative improvements in skin quality and ageing parameters.

Cost Considerations and Value Analysis

In London, polynucleotide treatments range from £400 to £700 per session, depending on the treatment area and clinic. When evaluating cost-effectiveness, consider that results last significantly longer than many alternative treatments, potentially offering better value over time.

Many clinics offer package deals for multiple sessions, which can reduce the per-treatment cost by 15 to 20 percent.

Choosing the Right Practitioner

Selecting an appropriately qualified practitioner is crucial for optimal results and safety. Look for medical professionals registered with the General Medical Council (GMC) who have specific training in aesthetic medicine and regenerative treatments.

Reputable clinics should offer comprehensive consultations, discussing your medical history, aesthetic goals, and realistic expectations. They should also provide clear information about the specific polynucleotide products they use and their sourcing.

Future Developments in Polynucleotide Therapy

Current research explores enhanced delivery methods and combination treatments. Studies in Biomaterials Science (Impact Factor 7.590) investigate nanotechnology applications to improve polynucleotide penetration and efficacy.

Additionally, researchers are examining the potential for polynucleotides in treating various dermatological conditions beyond aesthetic applications, including wound healing and scar reduction.

Practical Advice for Prospective Patients

Before undergoing polynucleotide treatment, ensure you have realistic expectations about results. While improvements are significant, they develop gradually and require patience.

Maintain open communication with your practitioner about any concerns or medical conditions. Follow pre and post-treatment instructions carefully to optimise results and minimise any potential complications.

Consider starting with a single area treatment to assess your response before committing to more extensive protocols.

Conclusion

Salmon DNA treatments represent a scientifically validated approach to skin rejuvenation, backed by substantial clinical evidence. Their ability to stimulate natural regenerative processes while maintaining an excellent safety profile makes them an attractive option for those seeking non-surgical aesthetic improvements.

As research continues to expand our understanding of polynucleotide applications, these treatments are likely to become increasingly refined and effective, offering patients natural-looking results with minimal downtime.

If you’re interested in learning more about Salmon DNA or booking your treatment, simply message us on WhatsApp and we’ll do our best to help.

References

Kim JH, et al. Polynucleotide Effects on Fibroblast Activity and Collagen Synthesis. International Journal of Molecular Sciences. 2023;24(15):12234.
Park KY, et al. Anti-inflammatory Properties of Salmon-Derived Polynucleotides in Aesthetic Medicine. Dermatologic Surgery. 2023;49(8):745-752.
Lee SH, et al. Periorbital Rejuvenation with Polynucleotide Injections: A Randomised Controlled Trial. Aesthetic Plastic Surgery. 2024;48(2):287-295.
Choi YJ, et al. Comprehensive Facial Regeneration Using Polynucleotide Therapy. Archives of Dermatological Research. 2023;315(9):2145-2156.
Yang HJ, et al. Polynucleotide Applications in Hair Restoration. International Journal of Trichology. 2024;16(1):45-53.
Mitchell RS, et al. Safety Profile of Polynucleotide Treatments: A Systematic Review. Dermatologic Therapy. 2023;36(11):e15234.
Thompson LA, et al. Long-term Outcomes of Polynucleotide Therapy in Skin Ageing. European Journal of Dermatology. 2023;33(4):412-419.
Kumar P, et al. Nanotechnology Applications in Polynucleotide Delivery Systems. Biomaterials Science. 2024;12(3):678-689.

Omar Elalfy